Molecular Docking Screens Using Comparative Models of Proteins
نویسندگان
چکیده
منابع مشابه
Molecular Docking Screens Using Comparative Models of Proteins
Two orders of magnitude more protein sequences can be modeled by comparative modeling than have been determined by X-ray crystallography and NMR spectroscopy. Investigators have nevertheless been cautious about using comparative models for ligand discovery because of concerns about model errors. We suggest how to exploit comparative models for molecular screens, based on docking against a wide ...
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ژورنال
عنوان ژورنال: Journal of Chemical Information and Modeling
سال: 2009
ISSN: 1549-9596,1549-960X
DOI: 10.1021/ci9003706